Genetic correlations with Age started oral contraceptive pill

Genetic correlation is estimated using LD-score regression. Full details of the correlation estimator can be found here.

In the tables, rg is the genetic correlation, and rp is the phenotypic correlation. Bonferroni significant p-values are displayed in bold, nominally significant p-values (p<0.05) are displayed in italics.

p-values less than or equal to 1e-308 are set to 1e-308 in the tables due to floating point precision. Exact p-values can be calculated from the Z-scores in the browser.

All

Volcano plot

ID Phenotype rg rg p rp
100001 Food weight 0.21 4.0e-03 0.00
100002 Energy 0.35 8.9e-05 0.02
100010 Portion size -0.11 1.3e-01 0.00
100011 Iron 0.38 6.8e-05 0.02
100016 Potassium 0.37 1.6e-05 0.03
100017 Magnesium 0.39 1.5e-06 0.03
1011 Frequency of light DIY in last 4 weeks -0.06 3.6e-01 -0.01
102 Pulse rate, automated reading -0.06 2.7e-02 0.01
1021 Duration of light DIY -0.15 6.8e-03 -0.02
1031 Frequency of friend/family visits 0.21 3.3e-08 0.03
1050 Time spend outdoors in summer -0.40 2.6e-33 -0.03
1060 Time spent outdoors in winter -0.22 1.5e-07 0.01
1070 Time spent watching television (TV) -0.37 8.8e-38 -0.05
1080 Time spent using computer 0.07 2.6e-02 -0.03
1090 Time spent driving -0.21 2.7e-07 -0.04
1100 Drive faster than motorway speed limit -0.07 5.8e-02 -0.05
110001 Invitation to complete online 24-hour recall dietary questionnaire, acceptance 0.31 2.4e-10 0.02
1110 Length of mobile phone use -0.32 4.3e-17 -0.08
1120 Weekly usage of mobile phone in last 3 months -0.51 1.9e-43 -0.09
1130 Hands-free device/speakerphone use with mobile phone in last 3 month -0.37 2.4e-15 -0.04
1140 Difference in mobile phone use compared to two years previously 0.05 5.2e-01 -0.01
1150_1 Usual side of head for mobile phone use: Left 0.06 3.4e-01 0.00
1150_2 Usual side of head for mobile phone use: Right 0.00 9.4e-01 0.00
1150_3 Usual side of head for mobile phone use: Equally left and right -0.12 4.3e-02 0.00
1160 Sleep duration 0.14 3.4e-04 0.02
1170 Getting up in morning -0.12 2.1e-04 -0.01
1180 Morning/evening person (chronotype) 0.03 2.3e-01 0.00
1190 Nap during day -0.06 8.8e-02 -0.01
1200 Sleeplessness / insomnia -0.27 3.7e-13 -0.04
1210 Snoring 0.14 1.2e-04 0.03
1220 Daytime dozing / sleeping (narcolepsy) -0.02 5.5e-01 0.00
1239 Current tobacco smoking -0.56 2.7e-48 -0.08
1249 Past tobacco smoking 0.45 7.8e-48 0.14
1259 Smoking/smokers in household -0.69 9.9e-20 -0.06
1269 Exposure to tobacco smoke at home -0.59 5.0e-18 -0.03
1279 Exposure to tobacco smoke outside home -0.44 1.7e-23 -0.03
1289 Cooked vegetable intake -0.10 1.6e-02 -0.01
129 Place of birth in UK - north co-ordinate -0.18 4.7e-03 0.03
1299 Salad / raw vegetable intake 0.03 4.7e-01 -0.02
1309 Fresh fruit intake 0.12 4.3e-04 0.02
1319 Dried fruit intake 0.29 8.8e-19 0.03
1329 Oily fish intake 0.16 2.1e-06 0.01
1339 Non-oily fish intake 0.10 3.8e-02 0.00
134 Number of self-reported cancers -0.19 2.7e-02 -0.02
1349 Processed meat intake -0.04 2.7e-01 0.01
135 Number of self-reported non-cancer illnesses -0.35 1.1e-27 -0.03
1359 Poultry intake -0.23 8.7e-08 -0.02
136 Number of operations, self-reported -0.43 5.1e-29 -0.07
1369 Beef intake -0.16 7.4e-05 -0.01
137 Number of treatments/medications taken -0.36 2.2e-28 -0.03
1379 Lamb/mutton intake -0.12 1.0e-03 -0.01
1389 Pork intake -0.19 6.3e-05 -0.01
1408 Cheese intake 0.35 2.3e-24 0.03
1418_1 Milk type used: Full cream -0.08 2.0e-01 0.00
1418_2 Milk type used: Semi-skimmed 0.12 2.6e-02 0.01
1418_3 Milk type used: Skimmed -0.03 5.9e-01 -0.01
1418_4 Milk type used: Soya -0.01 9.0e-01 0.00
1418_6 Milk type used: Never/rarely have milk -0.06 3.0e-01 -0.01
1428_0 Spread type: Never/rarely use spread 0.06 2.2e-01 -0.01
1428_1 Spread type: Butter/spreadable butter -0.07 5.1e-02 -0.02
1428_3 Spread type: Other type of spread/margarine 0.05 2.4e-01 0.02
1438 Bread intake 0.24 1.4e-09 0.05
1448_1 Bread type: White -0.35 3.1e-23 -0.03
1448_3 Bread type: Wholemeal or wholegrain 0.39 3.5e-22 0.02
1458 Cereal intake 0.37 3.1e-30 0.05
1468_3 Cereal type: Oat cereal (e.g. Ready Brek, porridge) 0.06 2.9e-01 0.00
1468_4 Cereal type: Muesli 0.35 2.2e-19 0.02
1468_5 Cereal type: Other (e.g. Cornflakes, Frosties) -0.39 3.7e-19 -0.01
1478 Salt added to food -0.22 4.4e-11 -0.05
1488 Tea intake 0.02 6.1e-01 0.01
1498 Coffee intake 0.05 1.5e-01 -0.01
1508_1 Coffee type: Decaffeinated coffee (any type) -0.02 7.5e-01 0.01
1508_2 Coffee type: Instant coffee -0.21 4.6e-06 -0.01
1508_3 Coffee type: Ground coffee (include espresso, filter etc) 0.20 9.0e-08 0.00
1518 Hot drink temperature 0.04 1.6e-01 0.00
1528 Water intake 0.03 3.7e-01 -0.01
1538_0 Major dietary changes in the last 5 years: No 0.41 1.7e-27 0.03
1538_1 Major dietary changes in the last 5 years: Yes, because of illness -0.35 6.9e-16 -0.01
1538_2 Major dietary changes in the last 5 years: Yes, because of other reasons -0.34 1.9e-11 -0.02
1548 Variation in diet -0.24 5.7e-09 -0.03
1558 Alcohol intake frequency. -0.14 1.3e-05 0.03
1568 Average weekly red wine intake 0.27 4.7e-12 0.01
1578 Average weekly champagne plus white wine intake 0.22 1.6e-06 -0.01
1588 Average weekly beer plus cider intake -0.26 4.2e-09 -0.04
1598 Average weekly spirits intake -0.38 1.6e-15 -0.04
1618 Alcohol usually taken with meals 0.40 8.0e-25 0.06
1628 Alcohol intake versus 10 years previously -0.32 1.2e-12 -0.02
1677 Breastfed as a baby 0.20 7.7e-05 0.00
1687 Comparative body size at age 10 0.00 9.2e-01 0.00
1697 Comparative height size at age 10 0.07 1.0e-02 -0.01
1757 Facial ageing 0.03 4.3e-01 0.00
1787 Maternal smoking around birth -0.54 1.1e-49 -0.08
1807 Father’s age at death 0.47 1.5e-23 0.03
1873 Number of full brothers -0.47 1.6e-16 0.00
1883 Number of full sisters -0.56 1.1e-21 -0.02
189 Townsend deprivation index at recruitment -0.45 3.4e-26 -0.03
1920 Mood swings -0.26 2.3e-13 -0.03
1930 Miserableness -0.23 3.5e-09 -0.04
1940 Irritability -0.11 3.1e-03 -0.02
1950 Sensitivity / hurt feelings -0.04 2.6e-01 -0.01
1960 Fed-up feelings -0.26 2.0e-11 -0.03
1970 Nervous feelings 0.23 2.7e-11 0.04
1980 Worrier / anxious feelings 0.18 2.7e-07 0.03
1990 Tense / ‘highly strung’ -0.07 8.2e-02 0.00
2000 Worry too long after embarrassment 0.16 1.4e-06 0.02
20002_1065 Non-cancer illness code, self-reported: hypertension -0.17 2.5e-08 -0.01
20002_1074 Non-cancer illness code, self-reported: angina -0.32 5.3e-12 -0.01
20002_1075 Non-cancer illness code, self-reported: heart attack/myocardial infarction -0.29 1.1e-09 -0.01
20002_1094 Non-cancer illness code, self-reported: deep venous thrombosis (dvt) -0.26 2.2e-04 -0.01
20002_1111 Non-cancer illness code, self-reported: asthma -0.19 7.7e-08 -0.02
20002_1138 Non-cancer illness code, self-reported: gastro-oesophageal reflux (gord) / gastric reflux -0.32 2.7e-06 -0.01
20002_1220 Non-cancer illness code, self-reported: diabetes -0.31 1.5e-14 0.00
20002_1226 Non-cancer illness code, self-reported: hypothyroidism/myxoedema -0.06 1.7e-01 -0.01
20002_1265 Non-cancer illness code, self-reported: migraine -0.05 3.1e-01 0.00
20002_1286 Non-cancer illness code, self-reported: depression -0.20 4.1e-04 -0.02
20002_1309 Non-cancer illness code, self-reported: osteoporosis -0.04 4.7e-01 0.00
20002_1387 Non-cancer illness code, self-reported: hayfever/allergic rhinitis 0.09 6.4e-02 0.01
20002_1465 Non-cancer illness code, self-reported: osteoarthritis -0.39 1.5e-15 -0.01
20002_1473 Non-cancer illness code, self-reported: high cholesterol -0.26 2.1e-10 -0.01
20002_1474 Non-cancer illness code, self-reported: hiatus hernia -0.25 1.0e-03 -0.01
20003_1140860696 Treatment/medication code: lisinopril -0.08 2.2e-01 0.00
20003_1140860806 Treatment/medication code: ramipril -0.20 1.6e-04 0.00
20003_1140861958 Treatment/medication code: simvastatin -0.26 1.6e-09 0.00
20003_1140861998 Treatment/medication code: ventolin 100micrograms inhaler -0.22 4.1e-05 -0.01
20003_1140864752 Treatment/medication code: lansoprazole -0.39 3.7e-09 -0.02
20003_1140865634 Treatment/medication code: omeprazole -0.52 4.6e-18 -0.02
20003_1140866738 Treatment/medication code: atenolol -0.15 7.9e-03 0.00
20003_1140868226 Treatment/medication code: aspirin -0.32 1.1e-11 0.00
20003_1140871310 Treatment/medication code: ibuprofen -0.23 5.8e-06 -0.03
20003_1140879802 Treatment/medication code: amlodipine -0.17 9.2e-04 -0.01
20003_1140884488 Treatment/medication code: diclofenac -0.34 1.7e-05 -0.02
20003_1140884600 Treatment/medication code: metformin -0.28 1.8e-12 0.00
20003_1140923346 Treatment/medication code: co-codamol -0.49 5.5e-15 -0.02
20003_1141146234 Treatment/medication code: atorvastatin -0.30 4.8e-07 0.00
20003_1141191044 Treatment/medication code: levothyroxine sodium -0.04 3.0e-01 0.00
20003_1141194794 Treatment/medication code: bendroflumethiazide -0.09 2.5e-02 0.00
20003_2038460150 Treatment/medication code: paracetamol -0.38 5.2e-24 -0.02
20015 Sitting height 0.10 3.5e-04 0.00
20016 Fluid intelligence score 0.31 5.6e-20 0.03
20018 Prospective memory result -0.19 4.0e-04 0.01
20022 Birth weight 0.08 1.6e-02 0.00
20023 Mean time to correctly identify matches 0.02 5.8e-01 0.00
20075 Home location at assessment - north co-ordinate (rounded) -0.26 1.9e-05 0.04
20077 Number of diet questionnaires completed 0.33 7.1e-11 0.02
2010 Suffer from ‘nerves’ 0.05 1.8e-01 0.00
20107_1 Illnesses of father: Heart disease 0.00 9.9e-01 0.00
20107_100 Illnesses of father: None of the above (group 1) 0.11 7.9e-02 0.00
20107_101 Illnesses of father: None of the above (group 2) 0.16 2.6e-02 0.01
20107_13 Illnesses of father: Prostate cancer 0.02 8.6e-01 0.00
20107_3 Illnesses of father: Lung cancer -0.35 2.3e-08 -0.02
20107_6 Illnesses of father: Chronic bronchitis/emphysema -0.42 6.7e-10 -0.02
20107_8 Illnesses of father: High blood pressure -0.03 6.1e-01 -0.01
20107_9 Illnesses of father: Diabetes -0.15 1.4e-02 -0.01
20110_1 Illnesses of mother: Heart disease -0.13 3.1e-02 -0.01
20110_100 Illnesses of mother: None of the above (group 1) 0.05 3.1e-01 0.00
20110_6 Illnesses of mother: Chronic bronchitis/emphysema -0.37 4.3e-08 -0.02
20110_8 Illnesses of mother: High blood pressure 0.00 9.8e-01 0.00
20110_9 Illnesses of mother: Diabetes -0.16 8.1e-04 -0.01
20111_1 Illnesses of siblings: Heart disease -0.36 4.8e-09 -0.01
20111_100 Illnesses of siblings: None of the above (group 1) 0.33 2.1e-16 0.02
20111_12 Illnesses of siblings: Severe depression -0.21 4.0e-04 -0.02
20111_8 Illnesses of siblings: High blood pressure -0.19 1.9e-05 -0.01
20111_9 Illnesses of siblings: Diabetes -0.37 7.9e-12 -0.01
20116_0 Smoking status: Never 0.52 2.5e-65 0.15
20116_1 Smoking status: Previous -0.39 8.0e-30 -0.11
20116_2 Smoking status: Current -0.56 1.4e-48 -0.08
20117_0 Alcohol drinker status: Never 0.06 2.9e-01 0.03
20117_1 Alcohol drinker status: Previous -0.35 2.4e-11 -0.01
20117_2 Alcohol drinker status: Current 0.17 2.2e-04 -0.02
20118_11 Home area population density - urban or rural: Scotland - Large Urban Area 0.21 5.4e-03 0.05
20126_0 Bipolar and major depression status: No Bipolar or Depression 0.26 7.7e-07 0.06
20127 Neuroticism score -0.06 1.1e-01 -0.01
20128 Number of fluid intelligence questions attempted within time limit 0.13 4.4e-03 -0.01
20150 Forced expiratory volume in 1-second (FEV1), Best measure 0.21 4.9e-13 0.01
20151 Forced vital capacity (FVC), Best measure 0.21 2.7e-13 0.01
20152 Reproduciblity of spirometry measurement using ERS/ATS criteria -0.15 4.6e-02 -0.02
20153 Forced expiratory volume in 1-second (FEV1), predicted 0.18 1.3e-08 0.01
20154 Forced expiratory volume in 1-second (FEV1), predicted percentage 0.22 1.3e-09 0.02
20160 Ever smoked -0.40 1.2e-31 -0.13
2020 Loneliness, isolation -0.27 5.6e-09 -0.02
2030 Guilty feelings -0.04 3.4e-01 -0.01
2040 Risk taking -0.40 1.2e-25 -0.05
20403 Amount of alcohol drunk on a typical drinking day -0.29 3.6e-07 -0.09
20414 Frequency of drinking alcohol 0.08 6.4e-02 -0.04
20416 Frequency of consuming six or more units of alcohol -0.21 8.4e-04 -0.10
20421 Ever felt worried, tense, or anxious for most of a month or longer -0.06 2.6e-01 -0.02
20425 Ever worried more than most people would in similar situation 0.06 2.8e-01 -0.01
20441 Ever had prolonged loss of interest in normal activities -0.24 4.6e-07 -0.06
20446 Ever had prolonged feelings of sadness or depression -0.19 4.2e-04 -0.04
20453 Ever taken cannabis -0.18 6.1e-05 -0.14
20458 General happiness 0.00 9.3e-01 0.00
20459 General happiness with own health -0.25 1.7e-07 -0.04
20460 Belief that own life is meaningful -0.03 5.9e-01 0.01
20479 Ever thought that life not worth living -0.09 9.9e-02 -0.04
20485 Ever contemplated self-harm -0.23 1.6e-04 -0.06
20487 Felt hated by family member as a child -0.35 3.1e-10 -0.06
20488 Physically abused by family as a child -0.43 1.1e-18 -0.06
20489 Felt loved as a child 0.34 4.8e-14 0.07
20491 Someone to take to doctor when needed as a child 0.48 1.6e-14 0.04
20495 Avoided activities or situations because of previous stressful experience in past month -0.11 1.2e-01 -0.03
20497 Repeated disturbing thoughts of stressful experience in past month -0.26 5.2e-07 -0.04
20498 Felt very upset when reminded of stressful experience in past month -0.26 3.0e-06 -0.05
20499 Ever sought or received professional help for mental distress -0.13 1.9e-02 -0.05
2050 Frequency of depressed mood in last 2 weeks -0.32 1.4e-14 -0.03
20500 Ever suffered mental distress preventing usual activities -0.26 7.8e-07 -0.06
20502 Ever had period extreme irritability -0.28 1.5e-07 -0.05
20505 Recent easy annoyance or irritability -0.17 1.9e-03 -0.03
20509 Recent inability to stop or control worrying -0.12 2.1e-02 -0.03
20510 Recent feelings of depression -0.23 8.5e-05 -0.03
20511 Recent poor appetite or overeating -0.41 1.3e-13 -0.06
20512 Recent feelings of foreboding -0.18 1.2e-03 -0.03
20514 Recent lack of interest or pleasure in doing things -0.29 1.6e-06 -0.04
20517 Trouble falling or staying asleep, or sleeping too much -0.27 1.1e-07 -0.05
20518 Recent changes in speed/amount of moving or speaking -0.33 1.1e-05 -0.04
20519 Recent feelings of tiredness or low energy -0.26 7.3e-08 -0.04
20520 Recent worrying too much about different things -0.13 3.5e-02 -0.02
20521 Belittlement by partner or ex-partner as an adult -0.48 6.4e-18 -0.09
20522 Been in a confiding relationship as an adult 0.00 9.5e-01 -0.02
20523 Physical violence by partner or ex-partner as an adult -0.68 5.3e-24 -0.10
20529 Victim of physically violent crime -0.11 1.1e-01 -0.02
20531 Victim of sexual assault -0.36 8.0e-08 -0.08
20536_0 Weight change during worst episode of depression: Stayed about the same or was on a diet 0.37 2.0e-07 0.05
20544_11 Mental health problems ever diagnosed by a professional: Depression -0.30 4.5e-08 -0.05
20544_15 Mental health problems ever diagnosed by a professional: Anxiety, nerves or generalized anxiety disorder -0.05 4.0e-01 -0.03
20546_3 Substances taken for depression: Medication prescribed to you (for at least two weeks) -0.22 5.4e-05 -0.06
20547_1 Activities undertaken to treat depression: Talking therapies, such as psychotherapy, counselling, group therapy or CBT -0.12 5.1e-02 -0.04
20548_1 Manifestations of mania or irritability: I was more talkative than usual -0.22 5.0e-03 -0.03
20548_2 Manifestations of mania or irritability: I was more restless than usual -0.34 3.6e-07 -0.04
20550_1 Activities undertaken to treat anxiety: Talking therapies, such as psychotherapy, counselling, group therapy or CBT -0.03 6.7e-01 -0.03
2060 Frequency of unenthusiasm / disinterest in last 2 weeks -0.38 2.2e-21 -0.04
2070 Frequency of tenseness / restlessness in last 2 weeks -0.26 6.2e-11 -0.03
2080 Frequency of tiredness / lethargy in last 2 weeks -0.32 5.4e-19 -0.03
2090 Seen doctor (GP) for nerves, anxiety, tension or depression -0.22 5.6e-09 -0.05
2100 Seen a psychiatrist for nerves, anxiety, tension or depression -0.29 1.2e-11 -0.03
21001 Body mass index (BMI) -0.29 2.3e-26 -0.05
21002 Weight -0.18 6.1e-12 -0.04
21021 Pulse wave Arterial Stiffness index -0.31 6.5e-08 -0.03
2110 Able to confide 0.05 2.4e-01 0.01
2129 Answered sexual history questions 0.19 1.2e-04 0.04
2139 Age first had sexual intercourse 0.84 5.1e-293 0.48
2149 Lifetime number of sexual partners -0.51 1.7e-57 -0.16
2159 Ever had same-sex intercourse -0.30 3.9e-05 -0.04
2178 Overall health rating -0.43 9.4e-53 -0.05
2188 Long-standing illness, disability or infirmity -0.38 1.6e-26 -0.03
2207 Wears glasses or contact lenses 0.16 3.6e-03 0.01
22126 Doctor diagnosed hayfever or allergic rhinitis 0.04 4.5e-01 0.00
22127 Doctor diagnosed asthma -0.08 1.1e-01 -0.02
2217 Age started wearing glasses or contact lenses -0.18 9.4e-08 -0.03
2227 Other eye problems -0.21 2.5e-03 -0.01
2237 Plays computer games -0.23 3.6e-13 -0.02
2247_0 Hearing difficulty/problems: No 0.15 5.5e-04 0.02
2247_1 Hearing difficulty/problems: Yes -0.15 5.8e-04 -0.02
22501 Year ended full time education 0.54 3.3e-36 0.08
22502 Cough on most days -0.06 3.6e-01 -0.02
22504 Bring up phlegm/sputum/mucus on most days -0.22 5.7e-03 -0.02
22506_113 Tobacco smoking: Ex-smoker -0.50 1.1e-21 -0.16
22506_114 Tobacco smoking: Never smoked 0.51 8.6e-28 0.18
2257 Hearing difficulty/problems with background noise -0.06 1.2e-01 -0.01
22601_23143401 Job coding: secondary school teacher or teaching professional (including head teacher) 0.25 1.6e-03 0.04
22606_2 Workplace very noisy: Often -0.59 1.8e-17 -0.05
22607_0 Workplace very cold: Rarely/never 0.17 1.9e-02 -0.02
22607_1 Workplace very cold: Sometimes -0.39 4.3e-09 -0.03
22608_2 Workplace very hot: Often -0.48 8.6e-09 -0.03
22609_2 Workplace very dusty: Often -0.46 1.3e-09 -0.03
22610_1 Workplace full of chemical or other fumes: Sometimes -0.49 2.3e-08 -0.04
22617_2314 Job SOC coding: Secondary education teaching professionals 0.26 1.1e-03 0.04
2267 Use of sun/uv protection 0.03 4.3e-01 -0.01
22704 Home location - north co-ordinate (rounded) -0.25 3.1e-05 0.04
2277 Frequency of solarium/sunlamp use -0.59 4.0e-37 -0.08
2296 Falls in the last year -0.33 2.1e-16 -0.02
2306 Weight change compared with 1 year ago -0.34 1.3e-05 -0.01
23098 Weight -0.17 1.0e-11 -0.04
23099 Body fat percentage -0.25 6.2e-22 -0.04
23100 Whole body fat mass -0.23 1.5e-19 -0.04
23101 Whole body fat-free mass -0.07 4.5e-03 -0.03
23102 Whole body water mass -0.07 3.7e-03 -0.03
23104 Body mass index (BMI) -0.29 4.2e-26 -0.05
23105 Basal metabolic rate -0.10 8.5e-05 -0.03
23106 Impedance of whole body 0.17 1.7e-09 0.03
23107 Impedance of leg (right) 0.09 6.0e-04 0.02
23108 Impedance of leg (left) 0.09 1.0e-03 0.02
23109 Impedance of arm (right) 0.20 7.5e-13 0.04
23110 Impedance of arm (left) 0.22 6.4e-15 0.04
23111 Leg fat percentage (right) -0.31 7.8e-32 -0.04
23112 Leg fat mass (right) -0.28 3.0e-26 -0.05
23113 Leg fat-free mass (right) -0.07 6.3e-03 -0.02
23114 Leg predicted mass (right) -0.07 6.3e-03 -0.02
23115 Leg fat percentage (left) -0.31 5.2e-31 -0.04
23116 Leg fat mass (left) -0.27 9.2e-26 -0.05
23117 Leg fat-free mass (left) -0.08 1.1e-03 -0.03
23118 Leg predicted mass (left) -0.08 1.0e-03 -0.03
23119 Arm fat percentage (right) -0.25 5.8e-21 -0.04
23120 Arm fat mass (right) -0.24 2.7e-20 -0.05
23121 Arm fat-free mass (right) -0.11 1.2e-05 -0.03
23122 Arm predicted mass (right) -0.11 1.7e-05 -0.03
23123 Arm fat percentage (left) -0.24 9.6e-20 -0.04
23124 Arm fat mass (left) -0.24 3.0e-19 -0.04
23125 Arm fat-free mass (left) -0.12 2.2e-06 -0.04
23126 Arm predicted mass (left) -0.13 7.0e-07 -0.04
23127 Trunk fat percentage -0.21 4.9e-16 -0.04
23128 Trunk fat mass -0.20 4.9e-15 -0.04
23129 Trunk fat-free mass -0.05 4.2e-02 -0.03
23130 Trunk predicted mass -0.05 4.4e-02 -0.03
2316 Wheeze or whistling in the chest in last year -0.44 8.1e-43 -0.04
2335 Chest pain or discomfort -0.34 6.5e-16 -0.03
2345 Ever had bowel cancer screening -0.08 1.3e-01 -0.04
2365 Ever had prostate specific antigen (PSA) test 0.08 1.9e-01 NA
2375 Relative age of first facial hair 0.10 4.0e-03 NA
2385 Relative age voice broke 0.14 8.5e-04 NA
2395_1 Hair/balding pattern: Pattern 1 -0.06 6.2e-02 NA
2395_2 Hair/balding pattern: Pattern 2 -0.08 9.3e-02 NA
2395_3 Hair/balding pattern: Pattern 3 0.12 1.9e-02 NA
2395_4 Hair/balding pattern: Pattern 4 0.05 1.0e-01 NA
24003 Nitrogen dioxide air pollution; 2010 -0.07 3.0e-01 0.00
24004 Nitrogen oxides air pollution; 2010 -0.19 7.7e-03 0.00
24006 Particulate matter air pollution (pm2.5); 2010 -0.20 4.3e-03 0.00
24016 Nitrogen dioxide air pollution; 2005 0.06 3.4e-01 -0.01
24017 Nitrogen dioxide air pollution; 2006 0.04 4.7e-01 0.00
24018 Nitrogen dioxide air pollution; 2007 0.09 1.2e-01 -0.01
24019 Particulate matter air pollution (pm10); 2007 0.09 1.5e-01 -0.02
2405 Number of children fathered -0.46 9.0e-18 NA
2415 Had major operations -0.33 4.1e-07 NA
2443 Diabetes diagnosed by doctor -0.29 5.8e-14 0.00
2463 Fractured/broken bones in last 5 years -0.11 4.8e-02 -0.01
2473 Other serious medical condition/disability diagnosed by doctor -0.28 5.9e-09 -0.02
2492 Taking other prescription medications -0.36 3.1e-26 -0.03
2634 Duration of heavy DIY -0.17 6.2e-03 -0.02
2644 Light smokers, at least 100 smokes in lifetime -0.39 2.6e-14 -0.10
2654_4 Non-butter spread type details: Soft (tub) margarine -0.41 3.6e-15 -0.03
2654_6 Non-butter spread type details: Olive oil based spread (eg: Bertolli) 0.32 5.3e-05 0.02
2664_3 Reason for reducing amount of alcohol drunk: Health precaution 0.24 2.0e-05 -0.01
2664_5 Reason for reducing amount of alcohol drunk: Other reason 0.04 4.6e-01 0.01
2714 Age when periods started (menarche) 0.13 5.8e-05 0.04
2724 Had menopause -0.14 9.4e-03 -0.03
2744 Birth weight of first child 0.15 3.4e-05 0.02
2754 Age at first live birth 0.72 1.7e-136 0.17
2764 Age at last live birth 0.64 4.4e-67 0.14
2814 Ever used hormone-replacement therapy (HRT) -0.60 9.9e-39 -0.05
2844 Had other major operations -0.35 2.4e-10 -0.04
2867 Age started smoking in former smokers 0.62 7.5e-32 0.13
2887 Number of cigarettes previously smoked daily -0.33 5.8e-11 -0.05
2926 Number of unsuccessful stop-smoking attempts -0.12 6.3e-02 -0.01
2966 Age high blood pressure diagnosed 0.00 9.4e-01 0.00
30000 White blood cell (leukocyte) count -0.17 1.0e-09 -0.04
30010 Red blood cell (erythrocyte) count 0.02 4.6e-01 0.01
30020 Haemoglobin concentration -0.06 2.7e-02 -0.01
30030 Haematocrit percentage -0.05 6.3e-02 -0.01
30040 Mean corpuscular volume -0.08 3.7e-04 -0.03
30050 Mean corpuscular haemoglobin -0.09 1.4e-04 -0.03
30060 Mean corpuscular haemoglobin concentration -0.04 2.1e-01 -0.01
30070 Red blood cell (erythrocyte) distribution width -0.07 8.2e-03 0.00
30080 Platelet count -0.03 3.1e-01 0.00
30090 Platelet crit -0.04 8.7e-02 0.00
30100 Mean platelet (thrombocyte) volume -0.02 4.6e-01 0.00
30110 Platelet distribution width -0.04 2.2e-01 0.00
30120 Lymphocyte count -0.17 2.0e-09 -0.05
30130 Monocyte count -0.09 4.4e-04 -0.02
30140 Neutrophill count -0.12 1.9e-05 -0.02
30150 Eosinophill count -0.10 3.0e-04 0.01
30160 Basophill count 0.00 9.6e-01 -0.05
30180 Lymphocyte percentage -0.05 1.1e-01 -0.03
30190 Monocyte percentage 0.04 1.8e-01 0.01
30200 Neutrophill percentage 0.04 1.9e-01 0.02
30210 Eosinophill percentage -0.03 2.5e-01 0.01
30220 Basophill percentage 0.03 4.4e-01 -0.01
30240 Reticulocyte percentage -0.20 2.8e-13 -0.04
30250 Reticulocyte count -0.19 8.8e-12 -0.04
30260 Mean reticulocyte volume -0.06 1.4e-02 -0.02
30270 Mean sphered cell volume -0.07 4.4e-03 -0.03
30280 Immature reticulocyte fraction -0.20 3.4e-11 -0.02
30290 High light scatter reticulocyte percentage -0.21 1.0e-14 -0.04
30300 High light scatter reticulocyte count -0.20 2.4e-13 -0.03
30500 Microalbumin in urine -0.14 8.0e-02 -0.01
30510 Creatinine (enzymatic) in urine -0.23 8.6e-13 -0.02
30520 Potassium in urine -0.12 4.8e-03 -0.01
30530 Sodium in urine -0.26 8.7e-16 -0.02
3062 Forced vital capacity (FVC) 0.21 1.1e-13 0.00
3063 Forced expiratory volume in 1-second (FEV1) 0.23 5.5e-15 0.01
3064 Peak expiratory flow (PEF) 0.12 1.8e-04 -0.01
3143 Ankle spacing width -0.08 4.3e-03 -0.02
3144 Heel Broadband ultrasound attenuation, direct entry -0.05 5.2e-02 -0.01
3147 Heel quantitative ultrasound index (QUI), direct entry -0.04 1.8e-01 0.00
3148 Heel bone mineral density (BMD) -0.03 1.9e-01 0.00
3393 Hearing aid user -0.24 1.2e-03 0.01
3526 Mother’s age at death 0.56 6.7e-16 0.03
3536 Age started hormone-replacement therapy (HRT) 0.42 1.4e-16 0.06
3571 Back pain for 3+ months -0.43 7.5e-10 -0.03
3581 Age at menopause (last menstrual period) 0.29 2.1e-12 0.03
3591 Ever had hysterectomy (womb removed) -0.50 1.1e-18 -0.03
3606 Chest pain or discomfort walking normally -0.47 3.7e-14 -0.04
3637 Frequency of other exercises in last 4 weeks -0.06 3.6e-01 -0.02
3761 Age hay fever, rhinitis or eczema diagnosed -0.14 8.8e-03 0.00
3799 Headaches for 3+ months -0.15 1.9e-02 -0.01
3849 Number of pregnancy terminations -0.35 5.2e-08 -0.08
398 Number of correct matches in round 0.19 1.1e-03 -0.01
399 Number of incorrect matches in round -0.01 7.0e-01 0.01
400 Time to complete round 0.06 5.5e-02 0.02
404 Duration to first press of snap-button in each round 0.00 9.2e-01 0.00
4079 Diastolic blood pressure, automated reading -0.08 4.1e-03 -0.01
4080 Systolic blood pressure, automated reading -0.04 1.5e-01 0.01
4100 Ankle spacing width (left) -0.08 1.3e-02 -0.02
4101 Heel broadband ultrasound attenuation (left) -0.05 1.8e-01 0.00
4104 Heel quantitative ultrasound index (QUI), direct entry (left) -0.03 2.9e-01 0.00
4105 Heel bone mineral density (BMD) (left) -0.03 2.7e-01 0.00
4106 Heel bone mineral density (BMD) T-score, automated (left) -0.03 2.9e-01 0.00
4119 Ankle spacing width (right) -0.10 2.4e-03 -0.02
4120 Heel broadband ultrasound attenuation (right) -0.02 4.9e-01 -0.01
41215_0 Detention categories: Informal, not formally detained -0.43 7.9e-06 -0.02
4123 Heel quantitative ultrasound index (QUI), direct entry (right) -0.02 6.1e-01 0.00
41231_1 Hospital episode type: General episode -0.58 3.9e-28 -0.06
41235 Spells in hospital -0.54 2.9e-30 -0.03
4124 Heel bone mineral density (BMD) (right) -0.01 6.7e-01 0.00
41248_1000 Destinations on discharge from hospital (recoded): Usual Place of residence -0.56 4.7e-39 -0.04
4125 Heel bone mineral density (BMD) T-score, automated (right) -0.02 6.1e-01 0.00
4194 Pulse rate -0.05 2.0e-01 0.00
4195 Pulse wave reflection index -0.14 8.3e-03 -0.03
4196 Pulse wave peak to peak time 0.38 4.6e-11 0.03
4260 Round of numeric memory test 0.13 5.9e-02 -0.01
4270 Volume level set by participant (left) -0.15 4.9e-02 -0.01
4282 Maximum digits remembered correctly 0.14 2.6e-02 0.00
4283 Number of rounds of numeric memory test performed 0.13 6.1e-02 -0.01
4288 Time to answer 0.16 8.2e-03 0.03
4290 Duration screen displayed -0.17 9.1e-06 0.02
4291 Number of attempts -0.18 4.7e-04 0.01
4526 Happiness 0.05 3.6e-01 0.01
4537 Work/job satisfaction 0.01 9.1e-01 0.02
4548 Health satisfaction -0.34 1.7e-14 -0.04
4559 Family relationship satisfaction -0.13 1.5e-02 -0.02
4570 Friendships satisfaction 0.05 3.3e-01 0.01
4581 Financial situation satisfaction -0.37 4.1e-14 -0.05
4598 Ever depressed for a whole week -0.26 6.6e-09 -0.04
46 Hand grip strength (left) 0.11 1.2e-04 0.02
4631 Ever unenthusiastic/disinterested for a whole week -0.24 9.3e-06 -0.05
4653 Ever highly irritable/argumentative for 2 days -0.45 8.5e-14 -0.07
4674 Private healthcare -0.17 1.8e-02 0.01
47 Hand grip strength (right) 0.14 2.3e-06 0.02
4717 Shortness of breath walking on level ground -0.40 1.5e-14 -0.03
4728 Leg pain on walking -0.46 1.5e-15 -0.04
48 Waist circumference -0.26 6.5e-22 -0.04
4803_0 Tinnitus: No, never 0.16 9.8e-04 0.00
4803_11 Tinnitus: Yes, now most or all of the time -0.06 3.5e-01 0.00
4825 Noisy workplace -0.48 4.1e-17 -0.02
4836 Loud music exposure frequency -0.25 6.9e-05 -0.06
49 Hip circumference -0.17 9.2e-11 -0.03
4957 FI3 : word interpolation 0.45 7.8e-21 0.04
4968 FI4 : positional arithmetic 0.40 1.6e-19 0.04
4979 FI5 : family relationship calculation 0.37 3.5e-09 0.02
4990 FI6 : conditional arithmetic 0.37 3.5e-17 0.04
50 Standing height 0.15 4.8e-09 0.01
5001 FI7 : synonym 0.33 2.2e-07 0.01
5012 FI8 : chained arithmetic 0.38 7.2e-14 0.04
5084 Spherical power (right) -0.19 2.9e-08 -0.03
5085 Spherical power (left) -0.21 1.9e-09 -0.04
5096 3mm weak meridian (left) -0.02 5.7e-01 0.00
5097 6mm weak meridian (left) -0.01 7.6e-01 -0.01
5098 6mm weak meridian (right) 0.01 7.6e-01 -0.01
5099 3mm weak meridian (right) 0.00 9.2e-01 0.00
5100 3mm weak meridian angle (right) 0.14 9.4e-02 0.00
5101 6mm weak meridian angle (right) 0.18 1.5e-02 0.00
5103 3mm weak meridian angle (left) 0.02 7.6e-01 0.01
5104 3mm strong meridian angle (left) -0.06 2.9e-01 0.00
5106 6mm strong meridian angle (right) 0.01 9.1e-01 0.00
5107 3mm strong meridian angle (right) -0.15 1.6e-02 0.00
5108 3mm asymmetry angle (right) 0.00 9.4e-01 0.00
5109 6mm asymmetry angle (right) 0.02 8.0e-01 0.00
5110 6mm asymmetry angle (left) -0.18 2.1e-02 -0.01
5111 3mm asymmetry angle (left) -0.15 3.8e-02 -0.02
5112 3mm cylindrical power angle (left) 0.02 7.6e-01 0.01
5114 6mm cylindrical power angle (right) 0.18 1.6e-02 0.00
5116 3mm cylindrical power (right) -0.03 5.3e-01 -0.01
5119 3mm cylindrical power (left) -0.12 3.0e-02 -0.02
5132 3mm strong meridian (right) 0.01 8.1e-01 0.00
5133 6mm strong meridian (right) 0.02 5.8e-01 0.00
5134 6mm strong meridian (left) 0.00 9.7e-01 0.00
5135 3mm strong meridian (left) 0.00 9.2e-01 0.00
5157 6mm asymmetry index (left) 0.01 8.5e-01 0.01
5158 6mm asymmetry index (right) 0.03 6.1e-01 0.01
5159 3mm asymmetry index (right) 0.01 8.9e-01 0.01
5201 logMAR, final (right) -0.26 7.2e-04 0.00
5254 Intra-ocular pressure, corneal-compensated (right) 0.08 3.7e-02 0.00
5255 Intra-ocular pressure, Goldmann-correlated (right) 0.04 3.8e-01 0.00
5256 Corneal hysteresis (right) -0.07 6.8e-02 0.00
5257 Corneal resistance factor (right) -0.03 4.2e-01 -0.01
5262 Intra-ocular pressure, corneal-compensated (left) 0.08 5.7e-02 0.00
5263 Intra-ocular pressure, Goldmann-correlated (left) 0.02 5.7e-01 0.00
5264 Corneal hysteresis (left) -0.07 8.4e-02 -0.01
5265 Corneal resistance factor (left) -0.04 3.4e-01 -0.01
5556 FI9 : concept interpolation 0.47 1.8e-15 0.06
5983 ECG, heart rate -0.01 8.8e-01 0.01
5984 ECG, load 0.25 2.8e-03 0.00
5993 ECG, number of stages in a phase 0.24 1.5e-02 -0.01
6032 Maximum workload during fitness test 0.23 2.7e-03 0.00
6033 Maximum heart rate during fitness test 0.08 2.1e-01 0.02
6138_1 Qualifications: College or University degree 0.46 1.3e-63 0.08
6138_100 Qualifications: None of the above -0.47 4.8e-51 -0.01
6138_2 Qualifications: A levels/AS levels or equivalent 0.48 9.3e-56 0.07
6138_3 Qualifications: O levels/GCSEs or equivalent 0.48 2.1e-35 0.02
6138_4 Qualifications: CSEs or equivalent -0.35 6.5e-13 -0.04
6138_5 Qualifications: NVQ or HND or HNC or equivalent -0.37 2.8e-10 -0.04
6138_6 Qualifications: Other professional qualifications eg: nursing, teaching 0.39 9.6e-26 0.05
6139_2 Gas or solid-fuel cooking/heating: A gas fire that you use regularly in winter time -0.03 6.8e-01 0.00
6139_3 Gas or solid-fuel cooking/heating: An open solid fuel fire that you use regularly in winter time 0.22 4.7e-06 -0.01
6141_1 How are people in household related to participant: Husband, wife or partner -0.09 7.2e-02 -0.01
6142_1 Current employment status: In paid employment or self-employed 0.29 4.2e-06 -0.01
6142_2 Current employment status: Retired 0.16 2.9e-02 0.02
6142_4 Current employment status: Unable to work because of sickness or disability -0.54 4.6e-35 -0.03
6143_1 Transport type for commuting to job workplace: Car/motor vehicle -0.42 4.5e-13 -0.04
6143_3 Transport type for commuting to job workplace: Public transport 0.40 2.3e-14 0.03
6143_4 Transport type for commuting to job workplace: Cycle 0.33 4.3e-12 0.03
6144_1 Never eat eggs, dairy, wheat, sugar: Eggs or foods containing eggs -0.08 2.5e-01 0.00
6144_4 Never eat eggs, dairy, wheat, sugar: Sugar or foods/drinks containing sugar -0.37 1.8e-22 -0.02
6144_5 Never eat eggs, dairy, wheat, sugar: I eat all of the above 0.39 5.5e-27 0.03
6145_1 Illness, injury, bereavement, stress in last 2 years: Serious illness, injury or assault to yourself -0.34 1.7e-08 -0.02
6145_100 Illness, injury, bereavement, stress in last 2 years: None of the above 0.40 1.8e-16 0.04
6145_6 Illness, injury, bereavement, stress in last 2 years: Financial difficulties -0.50 2.9e-32 -0.06
6146_100 Attendance/disability/mobility allowance: None of the above 0.61 5.1e-65 0.02
6146_2 Attendance/disability/mobility allowance: Disability living allowance -0.58 3.0e-48 -0.02
6146_3 Attendance/disability/mobility allowance: Blue badge -0.63 2.6e-46 -0.02
6147_1 Reason for glasses/contact lenses: For short-sightedness, i.e. only or mainly for distance viewing such as driving, cinema etc (called ‘myopia’) 0.29 1.4e-09 -0.01
6147_2 Reason for glasses/contact lenses: For long-sightedness, i.e. for distance and near, but particularly for near tasks like reading (called ‘hypermetropia’) -0.07 3.3e-01 -0.03
6147_3 Reason for glasses/contact lenses: For just reading/near work as you are getting older (called ‘presbyopia’) -0.10 3.0e-01 -0.04
6147_4 Reason for glasses/contact lenses: For ‘astigmatism’ 0.32 2.0e-05 -0.01
6149_1 Mouth/teeth dental problems: Mouth ulcers -0.08 8.1e-02 0.00
6149_100 Mouth/teeth dental problems: None of the above 0.41 4.6e-24 0.02
6149_3 Mouth/teeth dental problems: Bleeding gums -0.09 8.2e-02 -0.02
6149_4 Mouth/teeth dental problems: Loose teeth -0.37 3.0e-10 -0.02
6149_6 Mouth/teeth dental problems: Dentures -0.44 7.2e-31 -0.01
6150_1 Vascular/heart problems diagnosed by doctor: Heart attack -0.29 8.5e-10 -0.01
6150_100 Vascular/heart problems diagnosed by doctor: None of the above 0.20 1.3e-11 0.01
6150_2 Vascular/heart problems diagnosed by doctor: Angina -0.31 3.7e-11 -0.01
6150_4 Vascular/heart problems diagnosed by doctor: High blood pressure -0.16 8.6e-08 -0.01
6152_100 Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: None of the above 0.06 9.7e-02 0.01
6152_5 Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Blood clot in the leg (DVT) -0.24 5.1e-04 -0.01
6152_6 Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Emphysema/chronic bronchitis -0.44 1.4e-14 -0.01
6152_8 Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Asthma -0.18 2.1e-07 -0.02
6152_9 Blood clot, DVT, bronchitis, emphysema, asthma, rhinitis, eczema, allergy diagnosed by doctor: Hayfever, allergic rhinitis or eczema 0.09 8.2e-03 0.00
6153_1 Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Cholesterol lowering medication -0.31 2.7e-12 -0.01
6153_100 Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: None of the above 0.30 1.4e-13 0.02
6153_2 Medication for cholesterol, blood pressure, diabetes, or take exogenous hormones: Blood pressure medication -0.13 2.1e-04 -0.01
6154_1 Medication for pain relief, constipation, heartburn: Aspirin -0.31 5.1e-12 -0.01
6154_100 Medication for pain relief, constipation, heartburn: None of the above 0.39 2.9e-32 0.04
6154_2 Medication for pain relief, constipation, heartburn: Ibuprofen (e.g. Nurofen) -0.22 1.2e-06 -0.03
6154_3 Medication for pain relief, constipation, heartburn: Paracetamol -0.33 4.0e-20 -0.02
6154_5 Medication for pain relief, constipation, heartburn: Omeprazole (e.g. Zanprol) -0.42 9.3e-16 -0.02
6154_6 Medication for pain relief, constipation, heartburn: Laxatives (e.g. Dulcolax, Senokot) -0.33 3.0e-07 -0.02
6155_100 Vitamin and mineral supplements: None of the above 0.02 6.9e-01 0.01
6155_3 Vitamin and mineral supplements: Vitamin C 0.05 3.9e-01 0.00
6155_7 Vitamin and mineral supplements: Multivitamins +/- minerals -0.05 2.9e-01 -0.01
6157_100 Why stopped smoking: None of the above -0.20 4.5e-03 -0.02
6157_3 Why stopped smoking: Health precaution 0.33 1.3e-08 0.01
6159_1 Pain type(s) experienced in last month: Headache -0.16 4.9e-06 -0.01
6159_100 Pain type(s) experienced in last month: None of the above 0.39 8.2e-31 0.04
6159_3 Pain type(s) experienced in last month: Neck or shoulder pain -0.36 2.3e-19 -0.03
6159_4 Pain type(s) experienced in last month: Back pain -0.37 4.2e-22 -0.03
6159_5 Pain type(s) experienced in last month: Stomach or abdominal pain -0.30 2.1e-10 -0.03
6159_6 Pain type(s) experienced in last month: Hip pain -0.48 2.3e-22 -0.03
6159_7 Pain type(s) experienced in last month: Knee pain -0.35 7.1e-18 -0.03
6159_8 Pain type(s) experienced in last month: Pain all over the body -0.49 1.4e-13 -0.01
6160_1 Leisure/social activities: Sports club or gym 0.24 1.4e-07 0.01
6160_100 Leisure/social activities: None of the above -0.30 3.7e-14 -0.04
6160_2 Leisure/social activities: Pub or social club -0.25 1.2e-09 -0.05
6160_3 Leisure/social activities: Religious group 0.49 3.4e-38 0.12
6160_4 Leisure/social activities: Adult education class 0.35 7.2e-11 0.01
6160_5 Leisure/social activities: Other group activity 0.26 6.2e-08 0.03
6162_1 Types of transport used (excluding work): Car/motor vehicle -0.04 3.6e-01 -0.02
6162_2 Types of transport used (excluding work): Walk 0.40 3.5e-19 0.03
6162_3 Types of transport used (excluding work): Public transport 0.25 5.5e-09 0.03
6162_4 Types of transport used (excluding work): Cycle 0.31 1.4e-12 0.02
6164_1 Types of physical activity in last 4 weeks: Walking for pleasure (not as a means of transport) 0.45 2.8e-27 0.02
6164_100 Types of physical activity in last 4 weeks: None of the above -0.49 4.4e-27 -0.02
6164_2 Types of physical activity in last 4 weeks: Other exercises (eg: swimming, cycling, keep fit, bowling) 0.30 5.3e-15 0.01
6164_3 Types of physical activity in last 4 weeks: Strenuous sports 0.18 2.2e-04 0.01
6164_4 Types of physical activity in last 4 weeks: Light DIY (eg: pruning, watering the lawn) 0.31 1.9e-14 0.01
6164_5 Types of physical activity in last 4 weeks: Heavy DIY (eg: weeding, lawn mowing, carpentry, digging) 0.25 4.0e-10 0.01
6177_1 Medication for cholesterol, blood pressure or diabetes: Cholesterol lowering medication -0.26 1.2e-10 NA
6177_100 Medication for cholesterol, blood pressure or diabetes: None of the above 0.23 2.5e-09 NA
6177_2 Medication for cholesterol, blood pressure or diabetes: Blood pressure medication -0.17 1.5e-05 NA
6179_1 Mineral and other dietary supplements: Fish oil (including cod liver oil) 0.11 1.5e-02 0.00
6179_100 Mineral and other dietary supplements: None of the above -0.13 1.1e-03 0.00
6179_2 Mineral and other dietary supplements: Glucosamine 0.04 3.4e-01 -0.01
6179_3 Mineral and other dietary supplements: Calcium 0.08 1.9e-01 0.00
6179_4 Mineral and other dietary supplements: Zinc -0.13 4.1e-02 -0.01
670_1 Type of accommodation lived in: A house or bungalow 0.19 1.1e-03 0.00
680_1 Own or rent accommodation lived in: Own outright (by you or someone in your household) 0.51 4.2e-41 0.04
680_2 Own or rent accommodation lived in: Own with a mortgage -0.20 1.5e-03 -0.03
680_3 Own or rent accommodation lived in: Rent - from local authority, local council, housing association -0.58 9.7e-46 -0.03
699 Length of time at current address 0.36 5.9e-13 0.03
709 Number in household 0.08 1.9e-01 -0.02
728 Number of vehicles in household 0.02 6.8e-01 -0.05
738 Average total household income before tax 0.36 1.1e-27 0.01
767 Length of working week for main job -0.25 6.8e-05 -0.02
777 Frequency of travelling from home to job workplace -0.29 5.9e-06 -0.02
78 Heel bone mineral density (BMD) T-score, automated -0.04 1.8e-01 0.00
806 Job involves mainly walking or standing -0.37 1.9e-21 0.00
816 Job involves heavy manual or physical work -0.39 3.6e-26 -0.02
826 Job involves shift work -0.56 7.1e-24 -0.02
845 Age completed full time education 0.55 5.5e-62 0.06
864 Number of days/week walked 10+ minutes 0.04 2.9e-01 0.00
874 Duration of walks -0.22 2.4e-09 -0.01
884 Number of days/week of moderate physical activity 10+ minutes -0.11 4.5e-03 0.00
894 Duration of moderate activity -0.26 1.6e-08 -0.02
904 Number of days/week of vigorous physical activity 10+ minutes -0.10 3.3e-02 -0.01
914 Duration of vigorous activity -0.32 2.5e-10 -0.01
924 Usual walking pace 0.40 3.8e-36 0.02
93 Systolic blood pressure, manual reading 0.07 3.2e-01 0.00
94 Diastolic blood pressure, manual reading 0.12 1.1e-01 -0.01
943 Frequency of stair climbing in last 4 weeks 0.34 8.7e-17 0.01
971 Frequency of walking for pleasure in last 4 weeks -0.26 7.5e-09 -0.03
981 Duration walking for pleasure 0.28 1.2e-07 0.02
ASTHMA_MEDICATIO_COMORB Medication related adverse effects -0.21 1.3e-04 0.00
C3_BREAST_3 Malignant neoplasm of breast 0.05 4.1e-01 0.00
C3_DIGESTIVE_ORGANS Malignant neoplasm of digestive organs -0.16 9.4e-02 0.00
C3_MALE_GENITAL malignant neoplasm of male genital organs -0.01 8.7e-01 0.00
C3_OTHER_SKIN Other malignant neoplasms of skin 0.01 8.0e-01 -0.01
C3_PROSTATE Malignant neoplasm of prostate 0.01 8.8e-01 0.00
C3_SKIN Malignant neoplasm of skin 0.01 8.3e-01 0.00
C44 Diagnoses - main ICD10: C44 Other malignant neoplasms of skin -0.06 2.8e-01 0.00
C50 Diagnoses - main ICD10: C50 Malignant neoplasm of breast 0.04 6.0e-01 0.00
CARDIAC_ARRHYTM Cardiac arrhytmias, COPD co-morbidities -0.07 2.0e-01 0.00
COPD_EXCL COPD differential diagnosis -0.54 4.3e-19 -0.02
COX_ARTHROSIS Coxarthrosis arthrosis of hip -0.06 3.4e-01 0.00
D12 Diagnoses - main ICD10: D12 Benign neoplasm of colon, rectum, anus and anal canal -0.16 7.4e-03 -0.01
G56 Diagnoses - main ICD10: G56 Mononeuropathies of upper limb -0.29 1.3e-09 -0.01
G6_CARPTU Carpal tunnel syndrome -0.27 2.0e-08 -0.01
G6_EPIPAROX Episodal and paroxysmal disorders -0.30 2.7e-04 -0.02
G6_NERPLEX Nerve, nerve root and plexus disorders -0.36 1.4e-12 -0.02
H26 Diagnoses - main ICD10: H26 Other cataract -0.21 3.3e-04 0.00
H7_LENS Disorders of lens -0.20 1.4e-04 0.00
I20 Diagnoses - main ICD10: I20 Angina pectoris -0.39 4.3e-08 -0.01
I21 Diagnoses - main ICD10: I21 Acute myocardial infarction -0.28 6.4e-07 0.00
I25 Diagnoses - main ICD10: I25 Chronic ischaemic heart disease -0.21 4.7e-07 -0.01
I48 Diagnoses - main ICD10: I48 Atrial fibrillation and flutter -0.05 3.5e-01 0.00
I83 Diagnoses - main ICD10: I83 Varicose veins of lower extremities -0.13 7.4e-03 -0.01
I84 Diagnoses - main ICD10: I84 Haemorrhoids -0.27 2.1e-05 -0.01
I9_CHD Major coronary heart disease event -0.31 3.3e-10 -0.01
I9_CORATHER Coronary atherosclerosis -0.22 1.1e-07 -0.01
I9_DISVEINLYMPH Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified -0.14 4.4e-03 -0.01
I9_IHD Ischaemic heart disease, wide definition -0.28 9.0e-13 -0.01
I9_MI Myocardial infarction -0.26 1.6e-06 0.00
ICDMAIN_ANY_ENTRY Any ICDMAIN event in hilmo or causes of death -0.55 8.1e-38 -0.04
II_NEOPLASM Neoplasms -0.21 1.5e-03 -0.01
IX_CIRCULATORY Diseases of the circulatory system -0.40 4.2e-19 -0.02
K11_GALLBILPANC Disorders of gallbladder, biliary tract and pancreas -0.32 3.5e-07 -0.02
K11_HERNIA Hernia -0.28 4.6e-08 -0.01
K21 Diagnoses - main ICD10: K21 Gastro-oesophageal reflux disease -0.35 5.1e-07 -0.01
K22 Diagnoses - main ICD10: K22 Other diseases of oesophagus -0.13 8.7e-02 -0.01
K40 Diagnoses - main ICD10: K40 Inguinal hernia -0.01 8.8e-01 0.00
K44 Diagnoses - main ICD10: K44 Diaphragmatic hernia -0.42 1.1e-08 -0.01
K57 Diagnoses - main ICD10: K57 Diverticular disease of intestine -0.18 8.5e-05 -0.01
K80 Diagnoses - main ICD10: K80 Cholelithiasis -0.32 2.0e-06 -0.01
KNEE_ARTHROSIS Gonarthrosis arthrosis of knee -0.37 4.6e-14 -0.01
M13_ARTHROSIS Arthrosis -0.35 2.0e-15 -0.02
M13_DORSALGIA Dorsalgia -0.55 3.1e-17 -0.03
M13_HALLUXVALGUS Hallux valgus (acquired) -0.13 5.6e-02 -0.01
M13_LOWBACKPAIN Low back pain -0.52 3.4e-12 -0.02
M13_MENISCUSDERANGEMENTS Meniscus derangement -0.35 2.7e-07 -0.01
M13_OTHERJOINT Other joint disorders -0.48 1.9e-20 -0.02
M16 Diagnoses - main ICD10: M16 Coxarthrosis [arthrosis of hip] -0.06 3.4e-01 0.00
M17 Diagnoses - main ICD10: M17 Gonarthrosis [arthrosis of knee] -0.37 4.6e-14 -0.01
M20 Diagnoses - main ICD10: M20 Acquired deformities of fingers and toes -0.23 2.9e-04 -0.01
M23 Diagnoses - main ICD10: M23 Internal derangement of knee -0.37 1.5e-08 -0.01
M54 Diagnoses - main ICD10: M54 Dorsalgia -0.55 3.1e-17 -0.03
N39 Diagnoses - main ICD10: N39 Other disorders of urinary system -0.50 3.7e-10 -0.02
N81 Diagnoses - main ICD10: N81 Female genital prolapse -0.19 6.2e-03 -0.02
PULMONARYDG Other pulmonary diagnosis -0.54 2.4e-18 -0.02
PULM_MEDICATIO_COMORB Medication related adverse effects (Asthma/COPD) -0.23 1.2e-04 0.00
R07 Diagnoses - main ICD10: R07 Pain in throat and chest -0.48 6.2e-20 -0.02
R10 Diagnoses - main ICD10: R10 Abdominal and pelvic pain -0.51 9.7e-25 -0.03
R31 Diagnoses - main ICD10: R31 Unspecified haematuria -0.37 1.7e-05 -0.01
VII_EYE_ADNEXA Diseases of the eye and adnexa -0.25 1.7e-05 0.00
VI_NERVOUS Diseases of the nervous system -0.46 6.4e-16 -0.02
XIII_MUSCULOSKELET Diseases of the musculoskeletal system and connective tissue -0.52 2.3e-51 -0.04
XIV_GENITOURINARY Diseases of the genitourinary system -0.49 2.5e-19 -0.04
XIX_INJURY_POISON Injury, poisoning and certain other consequences of external causes -0.42 7.9e-16 -0.02
XI_DIGESTIVE Diseases of the digestive system -0.48 1.2e-34 -0.03
XVIII_MISCFINDINGS Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified -0.51 1.1e-32 -0.04

Males

Volcano plot

This phenotype is not significant or does not make sense for males.

Females

Volcano plot

This phenotype is not significant or does not make sense for females.